{"id":531,"date":"2025-04-03T14:48:21","date_gmt":"2025-04-03T14:48:21","guid":{"rendered":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/?p=531"},"modified":"2025-04-03T14:59:20","modified_gmt":"2025-04-03T14:59:20","slug":"from-lab-to-lifesaver-how-3d-muscle-models-are-rewriting-orphan-disease-rules","status":"publish","type":"post","link":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/from-lab-to-lifesaver-how-3d-muscle-models-are-rewriting-orphan-disease-rules\/","title":{"rendered":"From Lab to Lifesaver: How 3D Muscle Models Are Rewriting Orphan Disease Rules"},"content":{"rendered":"\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1920\" height=\"1280\" src=\"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-content\/uploads\/2025\/04\/lucas-vasques-9vnACvX2748-unsplash.jpg\" alt=\"\" class=\"wp-image-528\" srcset=\"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-content\/uploads\/2025\/04\/lucas-vasques-9vnACvX2748-unsplash.jpg 1920w, https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-content\/uploads\/2025\/04\/lucas-vasques-9vnACvX2748-unsplash-300x200.jpg 300w, https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-content\/uploads\/2025\/04\/lucas-vasques-9vnACvX2748-unsplash-1024x683.jpg 1024w, https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-content\/uploads\/2025\/04\/lucas-vasques-9vnACvX2748-unsplash-768x512.jpg 768w, https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-content\/uploads\/2025\/04\/lucas-vasques-9vnACvX2748-unsplash-1536x1024.jpg 1536w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/><\/figure>\n\n\n\n<p>Over&nbsp;<strong>300 million people<\/strong>&nbsp;worldwide suffer from rare diseases, many with no treatments. Traditional drug discovery ignores these conditions\u2014too niche, too risky. But what if you could test therapies on&nbsp;<strong>human muscle<\/strong>&nbsp;engineered to mirror exact disease biology?<\/p>\n\n\n\n<p>Myomaker Bio\u2019s platform does just that. We recently partnered with a biotech to screen 1,200 FDA-approved drugs for ALS using our&nbsp;<strong>neuromuscular junction (NMJ) models<\/strong>. Within weeks, we identified a repurposed cardiac drug that improved motor neuron survival by&nbsp;<strong>40%<\/strong>\u2014a breakthrough missed by animal studies.<\/p>\n\n\n\n<p>For orphan diseases, time isn\u2019t just money; it\u2019s lives. Our models cut preclinical timelines by&nbsp;<strong>50%<\/strong>, giving hope to underserved patients. Because every disease deserves a cure.<\/p>\n\n\n\n<p>Explore our <a href=\"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/services\">services<\/a>.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Over&nbsp;300 million people&nbsp;worldwide suffer from rare diseases, many with no treatments. Traditional drug discovery ignores these conditions\u2014too niche, too risky. But what if you could test therapies on&nbsp;human muscle&nbsp;engineered to mirror exact disease biology? Myomaker Bio\u2019s platform does just that. We recently partnered with a biotech to screen 1,200 FDA-approved drugs for ALS using our&nbsp;neuromuscular junction (NMJ) models. Within weeks, we identified a repurposed cardiac drug that improved motor neuron survival by&nbsp;40%\u2014a breakthrough missed by animal studies. For orphan diseases, time isn\u2019t just money; it\u2019s lives. Our models cut preclinical timelines by&nbsp;50%, giving hope to underserved patients. Because every disease deserves a cure. Explore our services.<\/p>\n","protected":false},"author":1,"featured_media":528,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_theme","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-531","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/posts\/531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/comments?post=531"}],"version-history":[{"count":4,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/posts\/531\/revisions"}],"predecessor-version":[{"id":538,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/posts\/531\/revisions\/538"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/media\/528"}],"wp:attachment":[{"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/media?parent=531"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/categories?post=531"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/brilliantreddev.co.uk\/myomakers-bio\/wp-json\/wp\/v2\/tags?post=531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}